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| − | <categorytree mode=all onlyroot="on" style="float:right; clear:right; margin-left:1ex; border:1px solid gray; padding:0.7ex; background-color:skyblue;">Antivirali</categorytree>
| + | Inibitori della polimerasi virale |
| − | =Inibitori della DNA polimerasi virale=
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| | ===Analoghi nucleosidici=== | | ===Analoghi nucleosidici=== |
| − | *[[Aciclovir]]
| + | [[Aciclovir]] |
| − | *[[Valaciclovir]]
| + | [[Valaciclovir]] |
| − | *[[Ganciclovir]]
| + | [[Ganciclovir]] |
| − | *[[Valganciclovir]]
| + | [[Valganciclovir]] |
| − | *[[Penciclovir]]
| + | [[Penciclovir]] |
| − | *[[Famciclovir]]
| + | [[Famciclovir]] |
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| − | <gallery widths=270px heights=170px perrow=3 caption="Strutture">
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| − | File:aciclovir.jpg|Aciclovir
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| − | file:Valaciclovir.jpg|Valaciclovir
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| − | File:ganciclovir.jpg|Ganciclovir
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| − | File:Valganciclovir.jpg|Valganciclovir
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| − | File:Penciclovir.jpg|Penciclovir
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| − | File:Famciclovir.jpg|Famciclovir
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| − | </gallery>
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| − |
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| − | ====meccanismo d'azione====
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| | | | |
| | ===Analoghi nucleotidici=== | | ===Analoghi nucleotidici=== |
| − | [[Cidofovir]]
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| − | <gallery widths=160px heights=160px perrow=1 caption="Struttura">
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| − | File:Cidofovir.jpg|Cidofovir
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| − | </gallery>
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| | | | |
| | ===Analogo del pirofosfato=== | | ===Analogo del pirofosfato=== |
| − | [[Foscarnet]]
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| − | <gallery widths=160px heights=160px perrow=1 caption="Struttura">
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| − | File:Foscarnet.jpg|Foscarnet
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| − | </gallery>
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| | | | |
| | =Inibitori della trascrittasi inversa= | | =Inibitori della trascrittasi inversa= |
| | ===Analoghi nucleosidici=== | | ===Analoghi nucleosidici=== |
| − | *[[Abacavir]]
| + | [[Abacavir]] |
| − | *[[Didanosina]]
| + | [[Didanosina]] |
| − | *[[Emtricitabina]]
| + | [[Emtricitabina]] |
| − | *[[Lamivudina]]
| + | [[Lamivudina]] |
| − | *[[Stavudina]]
| + | [[Stavudina]] |
| − | *[[Telbivudina]]
| + | [[Telbivudina]] |
| − | *[[Zalcitabina]]
| + | [[Zalcitabina]] |
| − | *[[Zidovudina]]
| + | [[Zidovudina]] |
| − | *[[Apricitabina]]
| + | [[Apricitabina]] |
| − | *[[Stampidina]]
| + | [[Stampidina]] |
| − | *[[Elvucitabina]]
| + | [[Elvucitabina]] |
| | + | |
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| − | <gallery widths=160px heights=160px perrow=4 caption="strutture">
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| − | File:Abacavir.jpg|Abacavir
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| − | File:Didanosina.jpg|Didanosina
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| − | File:Emtricitabina.jpg|Emtricitabina
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| − | File:Lamivudina.jpg|Lamivudina
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| − | File:Stavudina.jpg|Stavudina
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| − | File:Telbivudina.jpg|Telbivudina
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| − | File:Zalcitabina.jpg|Zalcitabina
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| − | File:Zidovudina.jpg|Zidovudina
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| − | </gallery>
| |
| | === Analoghi nucleotidici === | | === Analoghi nucleotidici === |
| − | *[[Tenofovir]]
| + | [[Tenofovir]] |
| − | <gallery widths=300px heights=120px perrow=1 caption="Struttura">
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| − | File:Tenofovir.jpg|Tenofovir
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| − | </gallery>
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| − | | |
| − | ===Inibitore non nucleosidico della trascrittasi inversa===
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| − | *[[Efavirenz]]
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| − | *[[Etravirina]]
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| − | *[[Nevirapina]]
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| | | | |
| − | <gallery widths=160px heights=160px perrow=3 caption="Strutture">
| + | ===Inibitore non nucleosidico della trascrittasi inversa (NNRTI)=== |
| − | File:Efavirenz.jpg|Efavirenz
| + | [[Efavirenz]] |
| − | File:Etravirina.jpg|Etravirina
| + | [[Etravirina]] |
| − | File:Nevirapina.jpg|Nevirapina
| + | [[Nevirapina]] |
| − | </gallery>
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| | | | |
| | =Inibitori della proteasi= | | =Inibitori della proteasi= |
| − | *[[Amprenavir]]
| + | [[Amprenavir]] |
| − | *[[Atazanavir]]
| + | [[Atazanavir]] |
| − | *[[Darunavir]]
| + | [[Darunavir]] |
| − | *[[Fosamprenavir]]
| + | [[Fosamprenavir]] |
| − | *[[Indinavir]]
| + | [[Indinavir]] |
| − | *[[Lopinavir]]
| + | [[Lopinavir]] |
| − | *[[Nelfinavir]]
| + | [[Nelfinavir]] |
| − | *[[Ritonavir]]
| + | [[Ritonavir]] |
| − | *[[Saquinavir]]
| + | [[Saquinavir]] |
| − | *[[Tipranavir]]
| + | [[Tipranavir]] |
| − | | |
| − | == meccanismo d'azione ==
| |
| − | Sono inibitori della proteasi, un enzima che processa e taglia le
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| − | grandi proteine precursori a dare le proteine strutturali e gli
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| − | enzimi necessari per la replicazione del virus.
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| − | | |
| − | Si formano quindi particelle di virus immature.
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| − | | |
| − | <gallery widths=300px heights=140px perrow=3 caption="Strutture">
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| − | File:Amprenavir.jpg|[[Amprenavir]]
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| − | File:Atazanavir.jpg|[[Atazanavir]]
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| − | File:Darunavir.jpg|[[Darunavir]]
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| − | File:Fosamprenavir.jpg|[[Fosamprenavir]]
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| − | File:Indinavir.jpg|[[Indinavir]]
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| − | File:Lopinavir.jpg|[[Lopinavir]]
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| − | File:Nelfinavir.jpg|[[Nelfinavir]]
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| − | File:Ritonavir.jpg|[[Ritonavir]]
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| − | File:Saquinavir.jpg|[[Saquinavir]]
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| − | File:Tipranavir.jpg|[[Tipranavir]]
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| − | </gallery>
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| | | | |
| | =Interferoni= | | =Interferoni= |
